Role of MAML1 in targeted therapy against the esophageal cancer stem cells

BACKGROUND: Esophageal cancer is the sixth-leading cause of cancer-related deaths worldwide. Cancer stem cells (CSCs) are the main reason for tumor relapse in esophageal squamous cell carcinoma (ESCC). The NOTCH pathway is important in preservation of CSCs, therefore it is possible to target such ce...

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Bibliografiska uppgifter
I publikationen:J Transl Med
Huvudupphovsmän: Moghbeli, Meysam, Mosannen Mozaffari, Hooman, Memar, Bahram, Forghanifard, Mohammad Mahdi, Gholamin, Mehran, Abbaszadegan, Mohammad Reza
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2019
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6469193/
https://ncbi.nlm.nih.gov/pubmed/30992079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-1876-5
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