Role of MAML1 in targeted therapy against the esophageal cancer stem cells

BACKGROUND: Esophageal cancer is the sixth-leading cause of cancer-related deaths worldwide. Cancer stem cells (CSCs) are the main reason for tumor relapse in esophageal squamous cell carcinoma (ESCC). The NOTCH pathway is important in preservation of CSCs, therefore it is possible to target such ce...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Moghbeli, Meysam, Mosannen Mozaffari, Hooman, Memar, Bahram, Forghanifard, Mohammad Mahdi, Gholamin, Mehran, Abbaszadegan, Mohammad Reza
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6469193/
https://ncbi.nlm.nih.gov/pubmed/30992079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-1876-5
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