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Microencapsulation of Salmonella-Specific Bacteriophage Felix O1 Using Spray-Drying in a pH-Responsive Formulation and Direct Compression Tableting of Powders into a Solid Oral Dosage Form

The treatment of enteric bacterial infections using oral bacteriophage therapy can be challenging since the harsh acidic stomach environment renders phages inactive during transit through the gastrointestinal tract. Solid oral dosage forms allowing site-specific gastrointestinal delivery of high dos...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Vinner, Gurinder K., Rezaie-Yazdi, Zahra, Leppanen, Miika, Stapley, Andrew G.F., Leaper, Mark C., Malik, Danish J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6469172/
https://ncbi.nlm.nih.gov/pubmed/30909381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph12010043
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