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Microencapsulation of Salmonella-Specific Bacteriophage Felix O1 Using Spray-Drying in a pH-Responsive Formulation and Direct Compression Tableting of Powders into a Solid Oral Dosage Form

The treatment of enteric bacterial infections using oral bacteriophage therapy can be challenging since the harsh acidic stomach environment renders phages inactive during transit through the gastrointestinal tract. Solid oral dosage forms allowing site-specific gastrointestinal delivery of high dos...

詳細記述

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書誌詳細
出版年:Pharmaceuticals (Basel)
主要な著者: Vinner, Gurinder K., Rezaie-Yazdi, Zahra, Leppanen, Miika, Stapley, Andrew G.F., Leaper, Mark C., Malik, Danish J.
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6469172/
https://ncbi.nlm.nih.gov/pubmed/30909381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph12010043
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