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Cholecystokinin-2 Receptor Targeting with Novel C-terminally Stabilized HYNIC-Minigastrin Analogs Radiolabeled with Technetium-99m

The high overexpression of cholecystokinin-2 receptors (CCK2R) in tumors, such as medullary thyroid carcinoma, allows for highly specific diagnostic and therapeutic targeting with radiolabeled peptide probes derived from natural ligands for the receptor. Based on the ideal imaging characteristics, h...

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Détails bibliographiques
Publié dans:Pharmaceuticals (Basel)
Auteurs principaux: Klingler, Maximilian, Rangger, Christine, Summer, Dominik, Kaeopookum, Piriya, Decristoforo, Clemens, von Guggenberg, Elisabeth
Format: Artigo
Langue:Inglês
Publié: MDPI 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6469167/
https://ncbi.nlm.nih.gov/pubmed/30650563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph12010013
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