Site-specific stabilization of minigastrin analogs against enzymatic degradation for enhanced cholecystokinin-2 receptor targeting

Minigastrin (MG) analogs show high affinity to the cholecystokinin-2 receptor (CCK2R) and have therefore been intensively studied to find a suitable analog for imaging and treatment of CCK2R-expressing tumors. The clinical translation of the radioligands developed thus far has been hampered by high...

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Bibliographische Detailangaben
Veröffentlicht in:Theranostics
Hauptverfasser: Klingler, Maximilian, Decristoforo, Clemens, Rangger, Christine, Summer, Dominik, Foster, Julie, Sosabowski, Jane K, von Guggenberg, Elisabeth
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2018
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5996369/
https://ncbi.nlm.nih.gov/pubmed/29896292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.24378
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