Bone marrow donor selection and characterization of MSCs is critical for pre-clinical and clinical cell dose production

BACKGROUND: Cell based therapies, such as bone marrow derived mesenchymal stem cells (BM-MSCs; also known as mesenchymal stromal cells), are currently under investigation for a number of disease applications. The current challenge facing the field is maintaining the consistency and quality of cells...

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Détails bibliographiques
Publié dans:J Transl Med
Auteurs principaux: Trivedi, Alpa, Miyazawa, Byron, Gibb, Stuart, Valanoski, Kristen, Vivona, Lindsay, Lin, Maximillian, Potter, Daniel, Stone, Mars, Norris, Philip J., Murphy, James, Smith, Sawyer, Schreiber, Martin, Pati, Shibani
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6469059/
https://ncbi.nlm.nih.gov/pubmed/30995929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-1877-4
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