Inhibition of CaMKIIα Activity Enhances Antitumor Effect of Fullerene C60 Nanocrystals by Suppression of Autophagic Degradation

Fullerene C60 nanocrystals (nano‐C60) possess various attractive bioactivities, including autophagy induction and calcium/calmodulin‐dependent protein kinase IIα (CaMKIIα) activation. CaMKIIα is a multifunctional protein kinase involved in many cellular processes including tumor progression; however...

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Veröffentlicht in:Adv Sci (Weinh)
Hauptverfasser: Xu, Jing, Wang, Hongsheng, Hu, Yi, Zhang, Yu Shrike, Wen, Longping, Yin, Fei, Wang, Zhuoying, Zhang, Yingchao, Li, Suoyuan, Miao, Yanyan, Lin, Binhui, Zuo, Dongqing, Wang, Gangyang, Mao, Min, Zhang, Tao, Ding, Jianxun, Hua, Yingqi, Cai, Zhengdong
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468974/
https://ncbi.nlm.nih.gov/pubmed/31016106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.201801233
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