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Targeting the mDia Formin-Assembled Cytoskeleton Is an Effective Anti-Invasion Strategy in Adult High-Grade Glioma Patient-Derived Neurospheres

High-grade glioma (HGG, WHO Grade III–IV) accounts for the majority of adult primary malignant brain tumors. Failure of current therapies to target invasive glioma cells partly explains the minimal survival advantages: invasive tumors lack easily-defined surgical margins, and are inherently more che...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Pettee, Krista M., Becker, Kathryn N., Alberts, Arthur S., Reinard, Kevin A., Schroeder, Jason L., Eisenmann, Kathryn M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468841/
https://ncbi.nlm.nih.gov/pubmed/30897774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11030392
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