The Novel Role of SOX2 as an Early Predictor of Cancer Risk in Patients with Laryngeal Precancerous Lesions

The SOX2 gene located at 3q26 is frequently amplified and overexpressed in multiple cancers, including head and neck squamous cell carcinomas (HNSCC). The tumor-promoting activity and involvement of SOX2 in tumor progression has been extensively demonstrated, thereby emerging as a promising therapeu...

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Publicat a:Cancers (Basel)
Autors principals: Granda-Díaz, Rocío, Menéndez, Sofía T., Pedregal Mallo, Daniel, Hermida-Prado, Francisco, Rodríguez, René, Suárez-Fernández, Laura, Vallina, Aitana, Sánchez-Canteli, Mario, Rodríguez, Aida, Fernández-García, M. Soledad, Rodrigo, Juan P., García-Pedrero, Juana M.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468607/
https://ncbi.nlm.nih.gov/pubmed/30823625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11030286
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