The Novel Role of SOX2 as an Early Predictor of Cancer Risk in Patients with Laryngeal Precancerous Lesions

The SOX2 gene located at 3q26 is frequently amplified and overexpressed in multiple cancers, including head and neck squamous cell carcinomas (HNSCC). The tumor-promoting activity and involvement of SOX2 in tumor progression has been extensively demonstrated, thereby emerging as a promising therapeu...

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Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Granda-Díaz, Rocío, Menéndez, Sofía T., Pedregal Mallo, Daniel, Hermida-Prado, Francisco, Rodríguez, René, Suárez-Fernández, Laura, Vallina, Aitana, Sánchez-Canteli, Mario, Rodríguez, Aida, Fernández-García, M. Soledad, Rodrigo, Juan P., García-Pedrero, Juana M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468607/
https://ncbi.nlm.nih.gov/pubmed/30823625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11030286
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