Cost-Efficient and Easy to Perform PCR-Based Assay to Identify Met Exon 14 Skipping in Formalin-Fixed Paraffin-Embedded (FFPE) Non-Small Cell Lung Cancer (NSCLC) Samples

MET is a receptor tyrosine kinase (RTK) that plays important roles in carcinogenesis. Despite being frequently overexpressed in cancer, clinical responses to targeting this receptor have been limited. Recently novel splicing mutations involving the loss of exon 14 (called METex14 skipping) have emer...

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Publicado no:Diagnostics (Basel)
Main Authors: O’Brien, Odharnaith, Wright, Mark C., O’Brien, Cathal, Geoghegan, Orla, Leonard, Niamh, Nicholson, Siobhan, Cuffe, Sinéad, Fabre, Aurelie, Jochum, Wolfram, Joerger, Markus, Gray, Steven G., Finn, Stephen P.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468531/
https://ncbi.nlm.nih.gov/pubmed/30669306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/diagnostics9010013
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