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Cost-Efficient and Easy to Perform PCR-Based Assay to Identify Met Exon 14 Skipping in Formalin-Fixed Paraffin-Embedded (FFPE) Non-Small Cell Lung Cancer (NSCLC) Samples

MET is a receptor tyrosine kinase (RTK) that plays important roles in carcinogenesis. Despite being frequently overexpressed in cancer, clinical responses to targeting this receptor have been limited. Recently novel splicing mutations involving the loss of exon 14 (called METex14 skipping) have emer...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Diagnostics (Basel)
Main Authors: O’Brien, Odharnaith, Wright, Mark C., O’Brien, Cathal, Geoghegan, Orla, Leonard, Niamh, Nicholson, Siobhan, Cuffe, Sinéad, Fabre, Aurelie, Jochum, Wolfram, Joerger, Markus, Gray, Steven G., Finn, Stephen P.
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468531/
https://ncbi.nlm.nih.gov/pubmed/30669306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/diagnostics9010013
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