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Comparison of miRNA expression patterns using total RNA extracted from matched samples of formalin-fixed paraffin-embedded (FFPE) cells and snap frozen cells

BACKGROUND: Archival formalin-fixed paraffin-embedded (FFPE) tissues have limited utility in applications involving analysis of gene expression due to mRNA degradation and modification during fixation and processing. This study analyzed 160 miRNAs in paired snap frozen and FFPE cells to investigate...

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Detalhes bibliográficos
Main Authors: Li, Jinghuan, Smyth, Paul, Flavin, Richard, Cahill, Susanne, Denning, Karen, Aherne, Sinead, Guenther, Simone M, O'Leary, John J, Sheils, Orla
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1914054/
https://ncbi.nlm.nih.gov/pubmed/17603869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-7-36
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