Comparison of miRNA expression patterns using total RNA extracted from matched samples of formalin-fixed paraffin-embedded (FFPE) cells and snap frozen cells

BACKGROUND: Archival formalin-fixed paraffin-embedded (FFPE) tissues have limited utility in applications involving analysis of gene expression due to mRNA degradation and modification during fixation and processing. This study analyzed 160 miRNAs in paired snap frozen and FFPE cells to investigate...

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Bibliographic Details
Main Authors: Li, Jinghuan, Smyth, Paul, Flavin, Richard, Cahill, Susanne, Denning, Karen, Aherne, Sinead, Guenther, Simone M, O'Leary, John J, Sheils, Orla
Format: Artigo
Language:Inglês
Published: BioMed Central 2007
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1914054/
https://ncbi.nlm.nih.gov/pubmed/17603869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-7-36
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