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Tyrosine kinase c-Abl couples RNA polymerase II transcription to DNA double-strand breaks

DNA is constantly exposed to endogenous and exogenous damage. Various types of DNA repair counteract highly toxic DNA double-strand breaks (DSBs) to maintain genome stability. Recent findings suggest that the human DNA damage response (DDR) utilizes small RNA species, which are produced as long non-...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Burger, Kaspar, Schlackow, Margarita, Gullerova, Monika
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468493/
https://ncbi.nlm.nih.gov/pubmed/30668775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz024
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