The Small Molecule Ephrin Receptor Inhibitor, GLPG1790, Reduces Renewal Capabilities of Cancer Stem Cells, Showing Anti-Tumour Efficacy on Preclinical Glioblastoma Models

Therapies against glioblastoma (GBM) show a high percentage of failure associated with the survival of glioma stem cells (GSCs) that repopulate treated tumours. Forced differentiation of GSCs is a promising new approach in cancer treatment. Erythropoietin-producing hepatocellular (Eph) receptors dri...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Gravina, Giovanni Luca, Mancini, Andrea, Colapietro, Alessandro, Delle Monache, Simona, Sferra, Roberta, Vitale, Flora, Cristiano, Loredana, Martellucci, Stefano, Marampon, Francesco, Mattei, Vincenzo, Beirinckx, Filip, Pujuguet, Philippe, Saniere, Laurent, Lorenzon, Giocondo, van der Aar, Ellen, Festuccia, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468443/
https://ncbi.nlm.nih.gov/pubmed/30871240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11030359
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