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Genes Located on 18q23 Are Epigenetic Markers and Have Prognostic Significance for Patients with Head and Neck Cancer

Loss of heterozygosity (LOH) on chromosome 18q23 is associated with significantly decreased survival in head and neck cancer. In agreement with such tumor suppressive roles, the loss of function of genes located in this region can be achieved through LOH and promotor hypermethylation. In this study,...

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Publicado en:Cancers (Basel)
Autores principales: Misawa, Kiyoshi, Kanazawa, Takeharu, Mochizuki, Daiki, Imai, Atsushi, Mima, Masato, Yamada, Satoshi, Morita, Kotaro, Misawa, Yuki, Shinmura, Kazuya, Mineta, Hiroyuki
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468360/
https://ncbi.nlm.nih.gov/pubmed/30901947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11030401
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