Staphylococcus aureus leukocidins target endothelial DARC to cause lethality in mice

The pathogenesis of Staphylococcus aureus is thought to depend on the production of pore-forming leukocidins that kill leukocytes and lyse erythrocytes. Two leukocidins, Leukocidin ED (LukED) and γ-Hemolysin AB (HlgAB), are necessary and sufficient to kill mice upon infection and toxin challenge. We...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cell Host Microbe
Main Authors: Lubkin, Ashira, Lee, Warren L., Alonzo, Francis, Wang, Changsen, Aligo, Jason, Keller, Matthew, Girgis, Natasha M., Reyes-Robles, Tamara, Chan, Rita, O’Malley, Aidan, Buckley, Peter, Vozhilla, Nikollaq, Vasquez, Marilyn T., Su, Johnny, Sugiyama, Michael, Yeung, Stephen T., Coffre, Maryaline, Bajwa, Sofia, Chen, Eric, Martin, Patricia, Kim, Sang Y., Loomis, Cynthia, Worthen, G. Scott, Shopsin, Bo, Khanna, Kamal M., Weinstock, Daniel, Lynch, Anthony Simon, Koralov, Sergei B., Loke, P’ng, Cadwell, Ken, Torres, Victor J.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468323/
https://ncbi.nlm.nih.gov/pubmed/30799265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2019.01.015
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker