Staphylococcus aureus leukocidins target endothelial DARC to cause lethality in mice

The pathogenesis of Staphylococcus aureus is thought to depend on the production of pore-forming leukocidins that kill leukocytes and lyse erythrocytes. Two leukocidins, Leukocidin ED (LukED) and γ-Hemolysin AB (HlgAB), are necessary and sufficient to kill mice upon infection and toxin challenge. We...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Host Microbe
Main Authors: Lubkin, Ashira, Lee, Warren L., Alonzo, Francis, Wang, Changsen, Aligo, Jason, Keller, Matthew, Girgis, Natasha M., Reyes-Robles, Tamara, Chan, Rita, O’Malley, Aidan, Buckley, Peter, Vozhilla, Nikollaq, Vasquez, Marilyn T., Su, Johnny, Sugiyama, Michael, Yeung, Stephen T., Coffre, Maryaline, Bajwa, Sofia, Chen, Eric, Martin, Patricia, Kim, Sang Y., Loomis, Cynthia, Worthen, G. Scott, Shopsin, Bo, Khanna, Kamal M., Weinstock, Daniel, Lynch, Anthony Simon, Koralov, Sergei B., Loke, P’ng, Cadwell, Ken, Torres, Victor J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468323/
https://ncbi.nlm.nih.gov/pubmed/30799265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2019.01.015
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados