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Double autoinhibition mechanism of signal transduction ATPases with numerous domains (STAND) with a tetratricopeptide repeat sensor

Upon triggering by their inducer, signal transduction ATPases with numerous domains (STANDs), initially in monomeric resting forms, multimerize into large hubs that activate target macromolecules. This process requires conversion of the STAND conserved core (the NOD) from a closed form encasing an A...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Lisa, María-Natalia, Cvirkaite-Krupovic, Virginija, Richet, Evelyne, André-Leroux, Gwenaëlle, Alzari, Pedro M, Haouz, Ahmed, Danot, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468293/
https://ncbi.nlm.nih.gov/pubmed/30788511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz112
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