A Gain-of-Function Mutation in the Second Tetratricopeptide Repeat of TFIIIC131 Relieves Autoinhibition of Brf1 Binding

The interaction between the tetratricopeptide repeat (TPR)-containing subunit of TFIIIC, TFIIIC131, and the TFIIB-related factor Brf1 represents a limiting step in the assembly of the RNA polymerase III (pol III) initiation factor TFIIIB. This assembly reaction is facilitated by dominant mutations t...

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Bibliografiska uppgifter
Huvudupphovsmän: Moir, Robyn D., Puglia, Karen V., Willis, Ian M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2002
Ämnen:
Transcriptional Regulation
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC134014/
https://ncbi.nlm.nih.gov/pubmed/12167707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.17.6131-6141.2002
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