Semaphorin‐3E attenuates intestinal inflammation through the regulation of the communication between splenic CD11C(+) and CD4(+)CD25(−) T‐cells

BACKGROUND AND PURPOSE: An alteration in the communication between the innate and adaptive immune cells is a hallmark of ulcerative colitis (UC). Semaphorin‐3E (SEMA3E), a secreted guidance protein, regulates various immune responses. EXPERIMENTAL APPROACH: We investigated the expression of SEMA3E i...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Kermarrec, Laëtitia, Eissa, Nour, Wang, Hongxing, Kapoor, Kunal, Diarra, Abdoulaye, Gounni, Abdelilah S., Bernstein, Charles N., Ghia, Jean‐Eric
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468259/
https://ncbi.nlm.nih.gov/pubmed/30736100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14614
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