Paracrine Induction of Epithelial-Mesenchymal Transition Between Colorectal Cancer Cells and its Suppression by a p53/miR-192/215/NID1 Axis

BACKGROUND & AIMS: Intratumor heterogeneity is a common feature of colorectal cancer (CRC). Here, we analyzed whether mesenchymal-like CRC cells promote the progression of epithelial-like CRC cells via paracrine mechanisms. METHODS: Six CRC cell lines that show an epithelial phenotype were treat...

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Bibliografiske detaljer
Udgivet i:Cell Mol Gastroenterol Hepatol
Main Authors: Rokavec, Matjaz, Bouznad, Nassim, Hermeking, Heiko
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2019
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468198/
https://ncbi.nlm.nih.gov/pubmed/30831320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2019.02.003
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