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Comparing Hydrolysis and Transglycosylation Reactions Catalyzed by Thermus thermophilus β-Glycosidase. A Combined MD and QM/MM Study

The synthesis of oligosaccharides and other carbohydrate derivatives is of relevance for the advancement of glycosciences both at the fundamental and applied level. For many years, glycosyl hydrolases (GHs) have been explored to catalyze the synthesis of glycosidic bonds. In particular, retaining GH...

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Détails bibliographiques
Publié dans:Front Chem
Auteurs principaux: Romero-Téllez, Sonia, Lluch, José M., González-Lafont, Àngels, Masgrau, Laura
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467970/
https://ncbi.nlm.nih.gov/pubmed/31024890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2019.00200
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