Chronic HIV-1 Infection Alters the Cellular Distribution of FcγRIIIa and the Functional Consequence of the FcγRIIIa-F158V Variant

Chronic HIV-infection modulates the expression of Fc gamma receptors (FcγRs) on immune cells and their antibody-dependent effector function capability. Given the increasingly recognized importance of antibody-dependent cellular cytotoxicity (ADCC) in HIV-specific immunity, we investigated the cellul...

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Détails bibliographiques
Publié dans:Front Immunol
Auteurs principaux: Phaahla, Ntando G., Lassaunière, Ria, Da Costa Dias, Bianca, Waja, Ziyaad, Martinson, Neil A., Tiemessen, Caroline T.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2019
Sujets:
Immunology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467939/
https://ncbi.nlm.nih.gov/pubmed/31024562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00735
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