Maslinic acid alleviates ischemia/reperfusion-induced inflammation by downregulation of NFκB-mediated adhesion molecule expression

Ischemia/reperfusion (I/R)-induced inflammation is associated with enhanced leukocyte rolling, adhesion and transmigration within the microcirculation. These steps are mediated by hypoxia-triggered signaling pathways, which upregulate adhesion molecule expression on endothelial cells and pericytes....

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Bibliographic Details
Published in:Sci Rep
Main Authors: Ampofo, Emmanuel, Berg, Julian J., Menger, Michael D., Laschke, Matthias W.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467883/
https://ncbi.nlm.nih.gov/pubmed/30992483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42465-7
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