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Depression stresses the immune response and promotes prostate cancer growth
Depression induces secretion of neuropeptide Y from prostate cancer cells which, in turn, recruits MDSCs to the tumor; tumor cells and MDSC secrete IL-6, which activates STAT3 within cancer cells. Prostate cancer samples from depressed patients reveal a similar phenotype, suggesting new treatment st...
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| Publicado no: | Clin Cancer Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6467802/ https://ncbi.nlm.nih.gov/pubmed/30670491 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-3980 |
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