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The role of a small molecule in the modulation of cell death signal transduction pathways
Inflammasomes activate caspase-1 in response to molecular signals from pathogens and other danger stimuli as a part of the innate immune response. A previous study discovered a small-molecule, 4-fluoro-N’-[1-(2-pyridinyl)ethylidene]benzohydrazide, which we named DN1, that reduces the cytotoxicity of...
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| Publicado no: | ACS Infect Dis |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6467792/ https://ncbi.nlm.nih.gov/pubmed/30354048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.8b00231 |
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