Ampullary Cancer: Evaluation of Somatic and Germline Genetic Alterations and Association with Clinical Outcomes

BACKGROUND: Ampullary carcinoma is a rare gastrointestinal cancer. Pathogenic germline alterations (PGA) in BRCA2 and potentially targetable somatic alterations (SA) in ERBB2 and ELF3 have been previously described in ampullary carcinoma. Memorial Sloan Kettering has implemented an opt-in strategy f...

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Veröffentlicht in:Cancer
Hauptverfasser: Wong, Winston, Lowery, Maeve A., Berger, Michael F., Kemel, Yelena, Taylor, Barry, Zehir, Ahmet, Srinivasan, Preethi, Bandlamudi, Chaitanya, Chou, Joanne, Capanu, Marinela, Varghese, Anna, Yu, Kenneth H., Iacobuzio-Donahue, Christine A., Shia, Jinru, Klimstra, David S., Jarnagin, William R., Stadler, Zsofia K., O’Reilly, Eileen M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467723/
https://ncbi.nlm.nih.gov/pubmed/30620386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.31951
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