Prospective Evaluation of Germline Alterations in Patients With Exocrine Pancreatic Neoplasms

BACKGROUND: Identification of pathogenic germline alterations (PGAs) has important clinical and therapeutic implications in pancreas cancer. We performed comprehensive germline testing (GT) in an unselected prospective cohort of patients with exocrine pancreatic neoplasms with genotype and phenotype...

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Bibliografski detalji
Izdano u:J Natl Cancer Inst
Glavni autori: Lowery, Maeve A, Wong, Winston, Jordan, Emmet J, Lee, Jonathan W, Kemel, Yelena, Vijai, Joseph, Mandelker, Diana, Zehir, Ahmet, Capanu, Marinela, Salo-Mullen, Erin, Arnold, Angela G, Yu, Kenneth H, Varghese, Anna M, Kelsen, David P, Brenner, Robin, Kaufmann, Erica, Ravichandran, Vignesh, Mukherjee, Semanti, Berger, Michael F, Hyman, David M, Klimstra, David S, Abou-Alfa, Ghassan K, Tjan, Catherine, Covington, Christina, Maynard, Hannah, Allen, Peter J, Askan, Gokce, Leach, Steven D, Iacobuzio-Donahue, Christine A, Robson, Mark E, Offit, Kenneth, Stadler, Zsofia K, O’Reilly, Eileen M
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
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Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186514/
https://ncbi.nlm.nih.gov/pubmed/29506128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djy024
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