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Prospective Evaluation of Germline Alterations in Patients With Exocrine Pancreatic Neoplasms

BACKGROUND: Identification of pathogenic germline alterations (PGAs) has important clinical and therapeutic implications in pancreas cancer. We performed comprehensive germline testing (GT) in an unselected prospective cohort of patients with exocrine pancreatic neoplasms with genotype and phenotype...

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Detalhes bibliográficos
Publicado no:J Natl Cancer Inst
Main Authors: Lowery, Maeve A, Wong, Winston, Jordan, Emmet J, Lee, Jonathan W, Kemel, Yelena, Vijai, Joseph, Mandelker, Diana, Zehir, Ahmet, Capanu, Marinela, Salo-Mullen, Erin, Arnold, Angela G, Yu, Kenneth H, Varghese, Anna M, Kelsen, David P, Brenner, Robin, Kaufmann, Erica, Ravichandran, Vignesh, Mukherjee, Semanti, Berger, Michael F, Hyman, David M, Klimstra, David S, Abou-Alfa, Ghassan K, Tjan, Catherine, Covington, Christina, Maynard, Hannah, Allen, Peter J, Askan, Gokce, Leach, Steven D, Iacobuzio-Donahue, Christine A, Robson, Mark E, Offit, Kenneth, Stadler, Zsofia K, O’Reilly, Eileen M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186514/
https://ncbi.nlm.nih.gov/pubmed/29506128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djy024
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