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Ruxolitinib: a targeted treatment option for patients with polycythemia vera

Polycythemia vera (PV) is a chronic myeloproliferative neoplasm characterized by erythrocytosis and the presence of Janus kinase (JAK) 2V617F or similar mutations. This review summarizes the pathophysiology of PV, the challenges associated with traditional treatment options, and the scientific ratio...

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Enregistré dans:
Détails bibliographiques
Publié dans:Blood Lymphat Cancer
Auteurs principaux: Vaddi, Kris, Verstovsek, Srdan, Kiladjian, Jean-Jacques
Format: Artigo
Langue:Inglês
Publié: Dove Medical Press 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467337/
https://ncbi.nlm.nih.gov/pubmed/31360077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/BLCTT.S101185
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