Critical involvement of a carbamylated lysine in catalytic function of class D β-lactamases

β-Lactamases are the resistance enzymes for β-lactam antibiotics, of which four classes are known. β-lactamases hydrolyze the β-lactam moieties of these antibiotics, rendering them inactive. It is shown herein that the class D OXA-10 β-lactamase depends critically on an unusual carbamylated lysine a...

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Bibliografske podrobnosti

izdano v:	Proc Natl Acad Sci U S A
Principais autores:	Golemi, Dasantila, Maveyraud, Laurent, Vakulenko, Sergei, Samama, Jean-Pierre, Mobashery, Shahriar
Format:	Artigo
Jezik:	Inglês
Izdano:	National Academy of Sciences 2001
Teme:	Biological Sciences
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC64673/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11724923/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.241442898
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