Critical involvement of a carbamylated lysine in catalytic function of class D β-lactamases
β-Lactamases are the resistance enzymes for β-lactam antibiotics, of which four classes are known. β-lactamases hydrolyze the β-lactam moieties of these antibiotics, rendering them inactive. It is shown herein that the class D OXA-10 β-lactamase depends critically on an unusual carbamylated lysine a...
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| Gepubliceerd in: | Proc Natl Acad Sci U S A |
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| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
2001
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC64673/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11724923/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.241442898 |
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