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Relationship Between Neutralizing Antibodies Against Adeno-Associated Virus in the Vitreous and Serum: Effects on Retinal Gene Therapy

PURPOSE: We determine the prevalence of neutralizing antibodies (NAbs) to adeno-associated virus (AAV) in the vitreous humor and serum of patients with vitreoretinal diseases and investigate the relationship between NAb titers in the vitreous humor and serum. METHODS: We analyzed NAbs to AAV serotyp...

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Detalhes bibliográficos
Publicado no:Transl Vis Sci Technol
Main Authors: Lee, Suhwan, Kang, Im Kyeung, Kim, Ji Hyun, Jung, Bok Kyoung, Park, Keerang, Chang, Heesoon, Lee, Joo Yong, Lee, Heuiran
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467092/
https://ncbi.nlm.nih.gov/pubmed/31016068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/tvst.8.2.14
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