The ionic layer is required for efficient dissociation of the SNARE complex by α-SNAP and NSF

The four-helical bundle soluble N-ethylmaleimide-sensitive fusion protein (NSF) attachment protein receptor (SNARE) complex that mediates intracellular membrane fusion events contains a highly conserved ionic layer at the center of an otherwise hydrophobic core. This layer has an undetermined functi...

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Bibliographic Details
Main Authors: Scales, Suzie J., Yoo, Bryan Y., Scheller, Richard H.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2001
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC64670/
https://ncbi.nlm.nih.gov/pubmed/11762430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.251547598
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