Exploring the Two Coupled Conformational Changes That Activate the Munc18-1/Syntaxin-1 Complex
Calcium-dependent synaptic vesicle exocytosis is mediated by SNARE complex formation. The transition from the Munc18-1/syntaxin-1 complex to the SNARE complex is catalyzed by the Munc13-1 MUN domain and involves at least two conformational changes: opening of the syntaxin-1 linker region and extensi...
Guardat en:
| Autors principals: | , , , , , , |
|---|---|
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Frontiers Media S.A.
2021-12-01
|
| Col·lecció: | Frontiers in Molecular Neuroscience |
| Matèries: | |
| Accés en línia: | https://www.frontiersin.org/articles/10.3389/fnmol.2021.785696/full |
| Etiquetes: |
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|