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Urinary Uromodulin Levels and UMOD Variants in Black South Africans with Hypertension-Attributed Chronic Kidney Disease

Uromodulin, the most abundant protein in urine, is synthesized in the thick ascending loop of Henle and distal convoluted tubules. Patients with chronic kidney disease (CKD) have reduced urinary uromodulin levels secondary to tubular damage. Genome wide association studies identified significant sin...

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Bibliographic Details
Published in:Int J Nephrol
Main Authors: Nqebelele, Nolubabalo Unati, Dickens, Caroline, Dix-Peek, Therese, Duarte, Raquel, Naicker, Saraladevi
Format: Artigo
Language:Inglês
Published: Hindawi 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6466913/
https://ncbi.nlm.nih.gov/pubmed/31065383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/8094049
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