Urinary Uromodulin Levels and UMOD Variants in Black South Africans with Hypertension-Attributed Chronic Kidney Disease

Uromodulin, the most abundant protein in urine, is synthesized in the thick ascending loop of Henle and distal convoluted tubules. Patients with chronic kidney disease (CKD) have reduced urinary uromodulin levels secondary to tubular damage. Genome wide association studies identified significant sin...

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Vydáno v:Int J Nephrol
Hlavní autoři: Nqebelele, Nolubabalo Unati, Dickens, Caroline, Dix-Peek, Therese, Duarte, Raquel, Naicker, Saraladevi
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6466913/
https://ncbi.nlm.nih.gov/pubmed/31065383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/8094049
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