The NuA4 acetyltransferase and histone H4 acetylation promote replication recovery after topoisomerase I-poisoning

BACKGROUND: Histone acetylation plays an important role in DNA replication and repair because replicating chromatin is subject to dynamic changes in its structures. However, its precise mechanism remains elusive. In this report, we describe roles of the NuA4 acetyltransferase and histone H4 acetylat...

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Vydáno v:Epigenetics Chromatin
Hlavní autoři: Noguchi, Chiaki, Singh, Tanu, Ziegler, Melissa A., Peake, Jasmine D., Khair, Lyne, Aza, Ana, Nakamura, Toru M., Noguchi, Eishi
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6466672/
https://ncbi.nlm.nih.gov/pubmed/30992049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-019-0271-z
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