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The NuA4 acetyltransferase and histone H4 acetylation promote replication recovery after topoisomerase I-poisoning

BACKGROUND: Histone acetylation plays an important role in DNA replication and repair because replicating chromatin is subject to dynamic changes in its structures. However, its precise mechanism remains elusive. In this report, we describe roles of the NuA4 acetyltransferase and histone H4 acetylat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Epigenetics Chromatin
Hauptverfasser: Noguchi, Chiaki, Singh, Tanu, Ziegler, Melissa A., Peake, Jasmine D., Khair, Lyne, Aza, Ana, Nakamura, Toru M., Noguchi, Eishi
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6466672/
https://ncbi.nlm.nih.gov/pubmed/30992049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-019-0271-z
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