Epitope-Specific Serological Assays for RSV: Conformation Matters

Respiratory syncytial virus (RSV) causes substantial morbidity and mortality in children and older adults. An effective vaccine must elicit neutralizing antibodies targeting the RSV fusion (F) protein, which exists in two major conformations, pre-fusion (pre-F) and post-fusion (post-F). Although 50%...

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Bibliographische Detailangaben
Veröffentlicht in:Vaccines (Basel)
Hauptverfasser: Phung, Emily, Chang, Lauren A., Morabito, Kaitlyn M., Kanekiyo, Masaru, Chen, Man, Nair, Deepika, Kumar, Azad, Chen, Grace L., Ledgerwood, Julie E., Graham, Barney S., Ruckwardt, Tracy J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6466065/
https://ncbi.nlm.nih.gov/pubmed/30813394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines7010023
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