Epitope-Specific Serological Assays for RSV: Conformation Matters

Respiratory syncytial virus (RSV) causes substantial morbidity and mortality in children and older adults. An effective vaccine must elicit neutralizing antibodies targeting the RSV fusion (F) protein, which exists in two major conformations, pre-fusion (pre-F) and post-fusion (post-F). Although 50%...

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Detalhes bibliográficos
Publicado no:Vaccines (Basel)
Main Authors: Phung, Emily, Chang, Lauren A., Morabito, Kaitlyn M., Kanekiyo, Masaru, Chen, Man, Nair, Deepika, Kumar, Azad, Chen, Grace L., Ledgerwood, Julie E., Graham, Barney S., Ruckwardt, Tracy J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6466065/
https://ncbi.nlm.nih.gov/pubmed/30813394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines7010023
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