Ketamine's Effects on the Glutamatergic and GABAergic Systems: A Proteomics and Metabolomics Study in Mice

Ketamine, a noncompetitive, voltage-dependent N-Methyl-D-aspartate receptor (NMDAR) antagonist, has been shown to have a rapid antidepressant effect and is used for patients experiencing treatment-resistant depression. We carried out a time-dependent targeted mass spectrometry-based metabolomics pro...

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Detalhes bibliográficos
Publicado no:Mol Neuropsychiatry
Main Authors: Weckmann, Katja, Deery, Michael J., Howard, Julie A., Feret, Renata, Asara, John M., Dethloff, Frederik, Filiou, Michaela D., Labermaier, Christiana, Maccarrone, Giuseppina, Lilley, Kathryn S., Mueller, Marianne, Turck, Christoph W.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2019
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6465744/
https://ncbi.nlm.nih.gov/pubmed/31019917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000493425
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