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Time-dependent metabolomic profiling of Ketamine drug action reveals hippocampal pathway alterations and biomarker candidates

Ketamine, an N-methyl-D-aspartate receptor (NMDAR) antagonist, has fast-acting antidepressant activities and is used for major depressive disorder (MDD) patients who show treatment resistance towards drugs of the selective serotonin reuptake inhibitor (SSRI) type. In order to better understand Ketam...

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Detalhes bibliográficos
Publicado no:Transl Psychiatry
Main Authors: Weckmann, K, Labermaier, C, Asara, J M, Müller, M B, Turck, C W
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259990/
https://ncbi.nlm.nih.gov/pubmed/25386958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2014.119
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