Defective Localization With Impaired Tumor Cytotoxicity Contributes to the Immune Escape of NK Cells in Pancreatic Cancer Patients

Tumor-infiltrating lymphocytes (TILs), found in patients with advanced pancreatic ductal adenocarcinoma (PDAC), are shown to correlate with overall survival (OS) rate. Although majority of TILs consist of CD8(+)/CD4(+) T cells, the presence of NK cells and their role in the pathogenesis of PDAC rema...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Lim, Seon Ah, Kim, Jungwon, Jeon, Seunghyun, Shin, Min Hwa, Kwon, Joonha, Kim, Tae-Jin, Im, Kyungtaek, Han, Youngmin, Kwon, Wooil, Kim, Sun-Whe, Yee, Cassian, Kim, Seong-Jin, Jang, Jin-Young, Lee, Kyung-Mi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6465515/
https://ncbi.nlm.nih.gov/pubmed/31024520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00496
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