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Blockade of HMGB1 signaling pathway by ethyl pyruvate inhibits tumor growth in diffuse large B-cell lymphoma

High mobility group box 1 (HMGB1) protein in the tumor microenvironment actively contributes to tumor progression but its role in diffuse large B-cell lymphoma (DLBCL) is unknown. The aim of this study was to determine the mechanism by which HMGB1 promotes tumor growth in DLBCL and whether blockade...

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Bibliographic Details
Published in:Cell Death Dis
Main Authors: Zhang, Tian, Guan, Xu-Wen, Gribben, John G., Liu, Feng-Ting, Jia, Li
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6465275/
https://ncbi.nlm.nih.gov/pubmed/30988279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1563-8
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