Cardiac inflammatory CD11b/c cells exert a protective role in hypertrophied cardiomyocyte by promoting TNFR(2)- and Orai3- dependent signaling

Early adaptive cardiac hypertrophy (EACH) is initially a compensatory process to optimize pump function. We reported the emergence of Orai3 activity during EACH. This study aimed to characterize how inflammation regulates store-independent activation of Orai3-calcium influx and to evaluate the funct...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Keck, Mathilde, Flamant, Mathilde, Mougenot, Nathalie, Favier, Sophie, Atassi, Fabrice, Barbier, Camille, Nadaud, Sophie, Lompré, Anne-Marie, Hulot, Jean-Sébastien, Pavoine, Catherine
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6465256/
https://ncbi.nlm.nih.gov/pubmed/30988334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42452-y
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