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Unveiling novel targets of paclitaxel resistance by single molecule long-read RNA sequencing in breast cancer

RNA sequencing has become one of the most common technology to study transcriptomes in cancer, whereas its length limits its application on alternative splicing (AS) events and novel isoforms. Firstly, we applied single molecule long-read RNA sequencing (Iso-seq) and de novo assembly with short-read...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Lian, Bi, Hu, Xin, Shao, Zhi-ming
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6465246/
https://ncbi.nlm.nih.gov/pubmed/30988345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42184-z
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