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Unveiling novel targets of paclitaxel resistance by single molecule long-read RNA sequencing in breast cancer

RNA sequencing has become one of the most common technology to study transcriptomes in cancer, whereas its length limits its application on alternative splicing (AS) events and novel isoforms. Firstly, we applied single molecule long-read RNA sequencing (Iso-seq) and de novo assembly with short-read...

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Detalles Bibliográficos
Publicado en:Sci Rep
Autores principales: Lian, Bi, Hu, Xin, Shao, Zhi-ming
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6465246/
https://ncbi.nlm.nih.gov/pubmed/30988345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42184-z
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