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Active Targeting of Cancer Cells by Nanobody Decorated Polypeptide Micelle with Bio-orthogonally Conjugated Drug

Polypeptides are promising carriers for chemotherapeutics: they have minimal toxicity, can be recombinantly synthesized with precise control over molecular weight, and enhance drug pharmacokinetics as self-assembled nanoparticles. Polypeptide-based systems also provide the ability to achieve active...

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Bibliographische Detailangaben
Veröffentlicht in:Nano Lett
Hauptverfasser: Costa, Simone A., Mozhdehi, Davoud, Dzuricky, Michael J., Isaacs, Farren J., Brustad, Eric M., Chilkoti, Ashutosh
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6465085/
https://ncbi.nlm.nih.gov/pubmed/30540482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.nanolett.8b03837
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