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The Weak Link: Optimization of the Ligand-Nanoparticle Interface To Enhance Cancer Cell Targeting by Polymer Micelles

Many promising targeting ligands are hydrophobic peptides, and these ligands often show limited accessibility to receptors, resulting in suboptimal targeting. A systematic study to elucidate the rules for the design of linkers that optimize their presentation on nanoparticles has not been carried ou...

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Detalhes bibliográficos
Publicado no:Nano Lett
Main Authors: Wang, Jing, Dzuricky, Michael, Chilkoti, Ashutosh
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6372105/
https://ncbi.nlm.nih.gov/pubmed/28853896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.nanolett.7b02225
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