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The Weak Link: Optimization of the Ligand-Nanoparticle Interface To Enhance Cancer Cell Targeting by Polymer Micelles

Many promising targeting ligands are hydrophobic peptides, and these ligands often show limited accessibility to receptors, resulting in suboptimal targeting. A systematic study to elucidate the rules for the design of linkers that optimize their presentation on nanoparticles has not been carried ou...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nano Lett
Prif Awduron: Wang, Jing, Dzuricky, Michael, Chilkoti, Ashutosh
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6372105/
https://ncbi.nlm.nih.gov/pubmed/28853896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.nanolett.7b02225
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