MC1R gene polymorphisms are associated with dysfunctional immune responses and wound infection after burn injury

BACKGROUND: Systemic inflammatory response syndrome (SIRS) is associated with organ failure and infectious complications after major burn injury. Recent evidence has linked melanocortin signaling to anti-inflammatory and wound-repair functions, with mutations in the melanocortin 1 receptor (MC1R) ge...

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Gepubliceerd in:J Surg Res
Hoofdauteurs: Carter, Damien W., Sood, Ravi F., Seaton, Max E., Muffley, Lara A., Honari, Shari, Hocking, Ann M., Arbabi, Saman A., Gibran, Nicole S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6464811/
https://ncbi.nlm.nih.gov/pubmed/30278967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2018.07.018
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